Publications
2020
43.
S. Kahraman, D. Manna, E. Dirice, B. Maji, J. Small, B. K. Wagner, A. Choudhary*, R. N. Kulkarni*
Life Science Alliance. In press
41.
K.C. Long, L. Alphey, G. J. Annas, C. S. Bloss, K. J. Campbell, J. Champer, C-H Chen, A. Choudhary, G. M. Church, J. P. Collins, K. L. Cooper, J. A. Delborne, O. R. Edwards, C. I. Emerson, K. Esvelt, S. W. Evans, R. M. Friedman, V. M. Gantz, F. Goud, S. Hartley, E. Heitman, J. Hemingway, H. Kanuka, J. Kuzma, J. V. Lavery, Y. Lee, M. Lorenzen, J. E. Lunshof, J. M. Marshall, P. W. Messer, C. Montell, K. A. Oye, M. J. Palmer, P. A. Papthanos, P. N. Paradkar, A. J. Piaggio, J. L. Rasgon, G. Rasic, L. Rudenko, J. R. Saah, M. J. Scott, J. T. Sutton, A. E. Vorsino, O. S. Akbari
Science. 2020, 370, 1417.
Highlighed in: EurekAlert, Phys.org, Science Daily
39.
K. Yang, M. Lee, P. A. Jones, S. S. Liu, A. Zhou, J. Xu, V. Sreekanth, J. L. Y. Wu, L.Vo, E. A. Lee, R. Pop, Y. Lee, B. K. Wagner, D. A. Melton, A. Choudhary*, J. M. Karp*
Science Advances. 2020, 6, eabc3207.
38.
V. Sreekanth, Q. Zhou, P. Kokkonda, H. Bermudez-Cabrera, D. Lim, B. Law, B. Holmes, S. Chaudhary, R. Pergu, B. Leger, J. A. Walker, D. Gifford, R. Sherwood, A. Choudhary. ACS Central Science. 2020, 6, 2228.
37.
D. Lim, V. Sreekanth, K. J. Cox, B. K. Law, B. K. Wagner, J. M. Karp, and A. Choudhary.
Nature Communications 2020, 11, 4043.
Highlighted in: Faculty of 1000, Nature Bioengineering Blog
36.
S. U. Siriwardena, D. N. P. M. Godage, V. M. Shoba, S. Lai, M. Shi, P. Wu, S. K. Chaudhary, S. L. Schreiber, and A. Choudhary
Journal of the American Chemical Society 2020, 142, 14052 – 14057
Highlighted in: BIOCENTURY, Faculty of 1000
35.
A. E. Modell, S.U. Siriwardena and A. Choudhary
Biochemistry 2020, 59, 1869-1870.
34.
V. L. D. Amo, B. S. Leger, K. J. Cox, S. Gill, A. L. Bishop, G. D. Scanlon, J. A. Walker, V. M. Gantz, A. Choudhary
Cell Reports 2020, 31,107841.
Highlighted in: GEN
33.
M. Lee, B. Maji, D. Manna, S. Kahraman, R. M. Elgamal, J. Small, P. Kokkonda, A. Vetere, J. M. Goldberg, S. J. Lippard, R. N. Kulkarni, B. K. Wagner and A. Choudhary
Journal of the American Chemical Society 2020, 142, 6477 – 6482.
2019
32.
A high-throughput platform to identify small-molecule inhibitors of CRISPR-Cas9
B. Maji, S. A. Gangopadhyay, M. Lee, M. Shi, P. Wu, R. Heler, B. Mok, D. Lim, S. U. Siriwardena, B. Paul, V. Dančík, A. Vetere, M. F. Mesleh, L. A. Marraffini, D. R. Liu, P. A. Clemons, B. K. Wagner and A. Choudhary
Cell 2019, 177, 1067-1079.
Highlighted in: Cell Press, Nature, Nature Methods, Nature Rev Drug Discovery, Broad Institute, Harvard Gazette, NewScientist, GEN, GenomeWeb, Phys.org, ScienceDaily, MIT Tech Review, In the Pipeline & several others.
2018
28.
Book Chapter: Kinase Inhibitor Drugs
© 2018 Wiley‐VCH Verlag GmbH & Co. KGaA.
2017
25.
Multidimensional chemogenic control of CRISPR-Cas9.
B. Maji, C. L. Moore, B. Zetsche, S. E. Volz, F. Zhang, M. D. Shoulders, A. Choudhary
Nature Chemical Biology 2017, 13, 9-11.
Highlighted in: News & Views
2016
2015
23.
Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling.
D. H-C. Chou,§ A. Vetere, § A. Choudhary, § S. S. Scully, M. Schenone, A. Tang, R. Gomez, S. M. Burns, M. Lundh, T. Vital, E. Comer, P. W. Faloon, V. Dančík, C. Ciarlo, J. Paulk, M. Dai, C. Reddy, H. Sun, M. Young, N. Donato, J. Jaffe, P. A. Clemons, M. Palmer, S. A. Carr, S. L. Schreiber and B. K. Wagner
Journal of the American Chemical Society 2015, 137, 7929 – 7934.
2014
2013
17.
Pyramidalization of a carbonyl C atom in (2S)-N-(selenoacetyl) proline methyl ester.
Acta Crystallographica Section E: Structure Reports Online 2013. 69, 805-806.
2012
15.
Synthesis of 5-Fluoro-and 5-Hydroxymethanoprolines via Lithiation of N-BOC-methanopyrrolidines. Constrained Cγ-Exo and Cγ-Endo Flp and Hyp Conformer Mimics.
G. R. Krow, M. D. Shoulders, R. Edupuganti, D. Gandla, F. Yu, P. E. Sonnet, M. Sender, A. Choudhary, C. DeBrosse, C. W. Ross III, P. Carroll and R. T. Raines
The Journal of Organic Chemistry 2012, 77, 5331 – 5344.
2011
10.
Synthesis of conformationally constrained 5-fluoro-and 5-hydroxymethanopyrrolidines. Ring-puckered mimics of gauche-and anti-3-fluoro-and 3-hydroxypyrrolidines.
G. R. Krow, R. Edupuganti, D. Gandla, F. Yu, M. Sender, P. E. Sonnet, M. J. Zdilla, C. DeBrosse, K. C. Cannon, C. W. Ross III and A. Choudhary, M. D. Shoulders and R. T. Raines.
The Journal of Organic Chemistry 2011, 76, 3626 – 3634.
2010
2009
2007
1.
Stereoselective synthesis of (−)-microcarpalide.
Tetrahedron Letters 2007, 48, 309-311.