Updates from the lab
In @angew_chem, we report Phosphorylation-inducing chimeric small molecules (PHICS) that rewired Protein Kinase C (PKC) to act at a new cellular location and phosphorylate non-native substrates or new sites on a substrate, resulting in new bioactivities. https://onlinelibrary.wiley.com/doi/10.1002/anie.202202770
The Best Scientists 🧵
I have heard a lot about the Best Scientists 🧑🔬
Maybe the best scientists…
make impactful discoveries,
publish in gilded journals,
garner millions in funding,
with lots of indirects.
And prizes, all the prizes🏆
And everybody respects them.
Out in @angew_chem our paper about the rational design of ionophores, the small molecules that can transport metal ions into cells. Ionophores have widespread applications but remain underdeveloped.
Ukraine is a global leader in the production of molecules used to fine-tune the design of new drugs. Russia’s attacks have put the industry and its scientists at risk. https://www.wsj.com/articles/ukraines-world-class-drug-molecule-industry-imperiled-by-russia-invasion-11647784800
04/09/19: Sophia is awarded NSF’s Graduate Research Fellowship. Congratulations!
03/02/19: Soumya will join start her new position as Scientist I at Intellia Therapeutics. Congratulations!
02/28/19: Our manuscript on precision control of CRISPR-Cas9 has been accepted for publicaiton in Angew Chem Int Ed. Congratulations to all the authors!
02/19/19: The lab welcomes Sierra and Nick, two high schools students from Arizona.
01/14/19: Our Perspective on precision control of CRISPR-Cas9 appears in “Future of Biochemistry” issue of ACS Biochemistry.
01/14/19: Undergrad student Axel Vera is accepted at MIT and Columbia to pursue graduate studies in chemistry. Congratulations!
01/11/19: Amit is invited to speak at Keystone Symposium on CRISPR.
01/02/19: Debasish becomes the 3rd postdoc from the lab to secure faculty positions. He will start his lab at IISER Bhopal. Congratulations!
12/28/18: Kurt’s and Hari’s paper on universal assay of CRISPR-nucleases is accepted in Chemical Sciences. Congratulations!
12/01/18: Ashley Modell from Bobby Arora’s lab will join us as a Postdoctoral fellow. Welcome!
10/15-27/18: Amit presents lab’s research at NCBS (Bangalore), IISc (Bangalore), IIT Kharagpur, and IIT Madras.
09/17/18: Amit is invited to speak at 2019 Yale Chemical Biology Symposium
08/23/18: Kurt, Soumya, Basudeb, and Brittany present posters at Cold Spring Harbor’s CRISPR-Cas9 meeting
08/22/18: Amit gives a talk at Cold Spring Harbor’s CRISPR-Cas meeting
08/20/18: Amit speaks at Precision Genome Engineering Symposium at ACS Boston meeting
08/14/18: Basudeb gives a talk at Nature Conference on Chemical Biology at NYU
08/13/18: Debasish, Miseon, Kurt, and Basudeb present posters at Nature Conference on Chemical Biology at NYU
08/18/18: Amit is invited to speak at UC San Diego
08/06/18: Ruth Elgamal joins lab as a Research Associate
07/23/18: Basudeb is invited as one of two student speakers at Nature Conference on Chemical Biology at NYU. Congratulations!
06/01/18: The Choudhary lab will host three summer students: Anna Dai (Middlesex School), Axel Vera (University of Puerto Rico), and Boomer Olson (Midwestern University). Welcome!
06/01/18: Veronika Shoba and Sachini Siriwardena will join us as postdoctoral fellow. Welcome!
05/14/18: Sophia Lai, a graduate student with Dept. of Chemistry and Chemical Biology, joins Choudhary lab. Welcome!
05/08/18: Amit gives a talk at Human Islet Research Consortia meeting. Miseon presents a poster.
04/22/18: The Choudhary lab is invited to contribute to the “Future of Biochemistry: The International issue” of Biochemistry
02/CRISPR Issue of ACS Chemical Biology is online now. Read Amit’s editorial here.
02/06/18: Peng Wu receives multiple faculty positions and decides to jon MPI Dortmund. Congratulations!
02/01/18: Laxmi and Sreekanth will join us as postdoctoral fellows. Welcome!
02/01/18: Amit is invited to organize mini-symposium on CRISPR at ACS Boston meeting (2018). Speaker line-up includes David Liu, Jim Collins, Dan Anderson, and Jennifer Doudna.
01/30/18: Amit is invited to speak at the inaugural symposium of Tata Institute of Genetics and Society at UCSD.
12/15/17: Amit is invited to speak at Horizon Discovery (Masterclass series) and NIH NHLBI on gene editing.
09/16/17: NIH will support our efforts to develop methods for beta-cell targeted cargo delivery. Weblink HERE.
09/14/17: Qingxuan and Rachit will join us as postdoctoral fellows. Welcome!
09/14/17: Our work on binge-eating snakes is highlighed by NIH Director. Weblink HERE.
07/12/17: Jonnell Small joins the lab as a Chemical Biology PhD student. Welcome!
06/04/17: Lab alumni Niha Putta will pursue undergraduate studies in Biochemistry at Brandeis University. Congratulations!
05/22/17: JDRF awards us Innovation grant to support our efforts towards beta-cell targeted genome editing
05/17/17: Our lab’s work on Burmese pythons is highlighted in the NEW YORK TIMES.
05/01/17: Miseon will join us as a postdoctoral fellow. Welcome!
04/02/17: Rachael receives PRISE fellowship and David Rockefeller International Experience grant. Congratulations!
04/15/17: Lab alumni Lucas Akin, who received offers from several top-notch gradaute programs, will join U of Illinois-UC. Sebasthian Santiago will pursue graduate studies at Yale University. Congratulations and all the best!
04/14/17: Daniel Palmieri will join us as a Research Associate. Welcome!
03/03/17: Donghyun will join us as a postdoctoral fellow. Welcome!
03/01/17: Rachel receives Harvard College Research Program Award. Congratulations!
02/24/17: Amit is invited to speak at CPhI, Philadelphia
01/31/17: Amit is invited to be a guest editor of a special issue of ACS Chemical Biology on CRISPR-Cas
01/30/17: Amit is invited to speak at Tim and McCullogh meeting in Mont-Tremblant, Quebec, Canada.
01/26/17: Amit is invited to speak at Merck & Co., Inc.
11/02/16: Amit is invited to speak at Keystone Symposia on Precison Genome Engineering.
10/04/16: Our snake project receives NIH Director’s Transformative Research Award.
09/23/16: Mengchao and Soumya will be joining us as a postdoctoral fellow. Welcome!
09/23/16: Our lab’s first paper is accepted for publication in Nature Chemical Biology!
09/21/16: Department of Defense awards a grant to support our efforts on CRISPR-Cas9.
08/26/16: Rachael and Rose join us as undergraduate researchers. Welcome!
06/10/16: Chris Moore wins the best poster award at the Bioorganic Gordon Conference. Congratulations!
06/09/16: The Choudhary lab will receive funding from NIAID/NIH to support CRISPR-Cas9 projects.
06/01/16: Niha Putta, a high school student, will joins us for summer. Welcome!
04/01/16: Amit is invited to speak at Bioorganic Gordon Conference about lab’s findings on CRISPR-Cas9.
03/18/16: Debasish Manna will join us as a postdoctoral fellow. Welcome!
12/20/15: Lab alumni Bishwajit Paul starts his independent laboratory at Bangalore University, India. Congratulations and all the best!
12/14/15: Amit gives an invited talk about exceptional organisms at the Broad Retreat.
11/16/15: Peng Wu will be joining us as a postdoctoral fellow. Welcome!
10/19/15: Erika Ding and Sebasthian Santiago join us as undergraduate researchers. Welcome!
06/11/15: Lucas Akin (Amgen Scholar) and Daniel Mirny join us as undergraduate researchers. Welcome!
06/08/15: Basudeb Maji joins us as a postdoctoral fellow. Welcome!
05/04/15: Our manuscript on the mechanism of action of BRD0476 is accepted for publication in JACS.
04/01/15: Juvenile Diabetes Research Foundation awards us their Innovation grant.
04/01/15: Our review on beta cells in Nature Reviews Drug Discovery is online.
06/01/14: Bishwajit Paul joins us as an Instructor of Medicine at Harvard Medical School. Welcome!
05/16/14: Amit is awarded Burroughs Wellcome Fund’s Career Award at the Scientific Interface.